Dedicated case managers, personalized support

We understand this can be a challenging time for you and your loved ones. ADVANCING Patient Support offers patients personalized assistance and support from ADC Therapeutics. Your dedicated case manager can provide the help you need so that you can focus on what’s important to you.

Visit to learn more.

Health Insurance Support

Helps you understand

  • If ZYNLONTA® is covered
  • What your costs may be
  • If there is are approvals or additional information needed prior to
    receiving therapy

Financial Support

  • If you are commercially insured and eligible, helps your healthcare provider enroll you in the copay program, in which you could pay as little as $0 per dosea
  • If you are uninsured or underinsured, assesses if you are eligible for the patient assistance program to cover your costs of therapy

Nursing Support

Free and available Monday–Friday (8 AM–8 PM ET)

  • Answers questions about ZYNLONTA®
  • Helps you plan conversations with your
    healthcare provider
  • Connects you to other services and support that are available to you

Important Note

Once your healthcare provider enrolls you, you will receive a welcome call from ADVANCING Patient Support. Save 1-855-690-0340 in your contacts so you recognize the number when called.

For more information, speak to your healthcare provider or to an ADVANCING Patient Support case manager at 1-855-690-0340, Monday–Friday (8 AM–8 PM ET).

aFor commercially insured patients, 18 years of age and older with coverage for ZYNLONTA®. Patients are not eligible if they participate in any federal or state healthcare program with prescription drug coverage, such as Medicaid, Medicare, Medicare Part D or Medicare Advantage plan, VA, DOD, or TRICARE. Excludes patients who are uninsured or full cash-paying. Maximum benefit per patient, per calendar year (1/1-12/31) is $25,000. Additional eligibility requirements and other restrictions apply. Visit

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What is ZYNLONTA®?

ZYNLONTA® is a prescription medicine used to treat adults with certain types of large B-cell lymphoma that has come back (relapsed) or that did not respond to previous treatment (refractory), who have already received two or more treatments for their cancer.

It is not known if ZYNLONTA® is safe and effective in children.

The approval of ZYNLONTA® is based on a type of response rate. There is an ongoing study to confirm the clinical benefit of ZYNLONTA®.

Important Safety Information

What are the possible side effects of ZYNLONTA®?

ZYNLONTA® may cause serious side effects, including:

  • Fluid Retention: Your body may hold too much fluid during treatment with ZYNLONTA®. This can be serious. Tell your healthcare provider if you develop new or worsening swelling or puffiness, weight gain, chest pain, shortness of breath, or trouble breathing.
  • Low blood cell counts (platelets, red blood cells, and white blood cells). Low blood cell counts are common with ZYNLONTA® but can also be serious or severe. Your healthcare provider will monitor your blood counts during treatment with ZYNLONTA®. Tell your healthcare provider right away if you get a fever of 100.4°F (38°C) or above, or any bruising or bleeding.
  • Infections: Serious infections, including infections that can cause death, have happened in people treated with ZYNLONTA®. Tell your healthcare provider right away if you have new or worsening signs or symptoms of infection, including: fever, chills, flu-like symptoms (cough, tiredness or weakness, and body aches), headache, breathing problems, or cuts or scrapes that are red, warm, swollen or painful.
  • Skin Reactions: Serious skin reactions have happened in people treated with ZYNLONTA®. Tell your healthcare provider if you get new or worsening skin reactions, including sensitivity to sunlight, skin rash, peeling, redness or irritation. You may burn more easily or get severe sunburns.

The most common side effects of ZYNLONTA® include:

  • feeling tired or weak
  • skin rash
  • swelling
  • nausea
  • muscle or joint pain
  • increase in blood sugar (hyperglycemia)
  • changes in certain blood or laboratory tests

ZYNLONTA® may cause fertility problems in males which may affect your ability to father children. Talk to your healthcare provider if this is a concern for you. These are not all of the possible side effects of ZYNLONTA®.  Call your healthcare provider for medical advice about side effects.

What should I avoid while receiving ZYNLONTA®?

Avoid or limit your exposure to sunlight, including sunlight through glass, such as buildings or vehicle windows and artificial sunlight such as sunlamps or tanning beds. Exposure to sunlight during treatment with ZYNLONTA® can cause skin reaction or rash. Use sun protection measures such as sunscreen and wear loose-fitting clothes that cover your skin while out in sunlight.

Before you receive ZYNLONTA®, tell your healthcare provider about all of your medical conditions, including if you:

  • have an active infection or have had one recently.
  • have liver problems.
  • are pregnant or plan to become pregnant. ZYNLONTA® can harm your unborn baby.

    Females who can become pregnant:

    • Your healthcare provider may do a pregnancy test before starting treatment with ZYNLONTA®.
    • You should use effective birth control (contraception) during treatment with ZYNLONTA® and for 9 months after the last dose of ZYNLONTA®. Talk to your healthcare provider about effective birth control. Tell your healthcare provider right away if you become pregnant or think that you are pregnant during treatment with ZYNLONTA®.

    Males with female partners who can become pregnant:

    • You should use effective birth control (contraception) during treatment with ZYNLONTA® and for 6 months after the last dose of ZYNLONTA®.
  • are breastfeeding or plan to breastfeed. It is not known if ZYNLONTA® passes into breast milk. Do not breastfeed during treatment with ZYNLONTA® and for 3 months after the last dose of ZYNLONTA®.

Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of them to show your healthcare provider or pharmacist when you get new medicine.

You may report side effects to the FDA at  (800) FDA-1088 or You may also report side effects to ADC Therapeutics at 1-855-690-0340.

Please see the full Prescribing Information for ZYNLONTA®, including Patient Information, for additional Important Safety Information.