ZYNLONTA®: Focus on time between treatments
ZYNLONTA® (loncastuximab tesirine-lpyl) is given through a needle placed in the vein (intravenous, or IV, infusion) at a clinic or infusion center.
ZYNLONTA® was specifically studied in adult patients who needed their next diffuse large B-cell lymphoma (DLBCL) therapy, after trying 2 or more past therapies.
Diffuse Large B-Cell Lymphoma (DLBCL) — A type of B-cell non-Hodgkin lymphoma (cancer of the immune system) that is usually aggressive (fast-growing). It is the most common type of non-Hodgkin lymphoma, and is marked by rapidly growing tumors in the lymph nodes, spleen, liver, bone marrow, or other organs.
ZYNLONTA® worked in 48% of people in the trial. And for some it worked in about 1 month*
*In a clinical trial, 145 patients with DLBCL that has come back (relapsed) or did not respond to previous therapy (refractory) were treated with ZYNLONTA® to see how well it worked. Out of 145 people, 70 saw anti-cancer results. The median time that it took for half of people to respond was 1.3 months. It took the other half longer to respond, up to 8.1 months.
Learn about ZYNLONTA® clinical trial results.
Schedule your infusion every 3 weeks
an intravenous (IV) infusion
Your doctor will decide how many therapies you need. You’ll work with office staff to figure out the best schedule for you.
Your doctor may give you medicine before each infusion to decrease your chance of side effects.
Your doctor may give you a steroid before ZYNLONTA®
Before each ZYNLONTA® treatment, you may have to take a prescription steroid (dexamethasone) to lower your chance of side effects.
Your doctor will let you know if this is needed. The steroid may be given as an oral medication or IV infusion.
- for 3 days
starting the day
Tip: Set a reminder on your phone about your therapy/therapies.
This way you can plan around your schedule
What to do if you miss a dose
Alert your doctor’s office right away to talk about your options.
Your doctor may change your treatment schedule
If you have severe side effects, your doctor may:
Change your dose
- Your doctor will also do blood tests regularly to check for side effects and keep an eye on your response to treatment while you’re on ZYNLONTA®
- You will be monitored for infusion site reactions, infections, and skin reactions. You may also need CT scans to monitor the cancer