Savings, Support & Resources

ADC Therapeutics, the makers of ZYNLONTA®
(loncastuximab tesirine-lpyl), are here to help you

Savings, Support & Resources

ADC Therapeutics, the makers of ZYNLONTA®
(loncastuximab tesirine-lpyl), are here to help you

Not an actual patient.

Reach out to dedicated case managers for support

Advancing Patient Support Program icon

We understand that you may have questions about your new treatment. ADVANCING Patient Support offers patients personalized assistance from ADC Therapeutics (the makers of ZYNLONTA®). Your personal case manager will be trained on your specific case, so they can provide you with the help and support you need.

Visit ADVANCINGPatientSupport.com to learn more.

You could qualify for a $0 Copay for ZYNLONTA® Treatment*

*For commercially insured patients, 18 years of age and older with coverage for ZYNLONTA®. Patients are not eligible if they participate in any federal or state healthcare program with prescription drug coverage, such as Medicaid, Medicare, Medicare Part D or Medicare Advantage plan, VA, DOD, or TRICARE. Excludes patients who are uninsured or full cash-paying. Maximum benefit per patient, per calendar year (1/1-12/31) is $25,000. Additional eligibility requirements and other restrictions apply. Visit ADVANCINGPatientSupport.com/copay-terms-conditions.

Health insurance support icon

Health insurance support

With everything on your mind, it’s great to have a professional help you sort it all out. When you enroll in ADVANCING Patient Support, your dedicated case manager can help you understand:

  • Whether or not ZYNLONTA® is covered under your plan
  • What your costs may be
  • What, if any, approvals or additional information you need prior to receiving therapy
Financial support icon

Financial support

We want you to be able to think less about how you are paying for your treatment so you can stay focused on your health and your future. ADVANCING Patient Support can help, by helping your doctor’s office enroll you in the copay program.

If you’re commercially insured

If you are commercially insured and eligible, ADVANCING Patient Support can help your doctor’s office enroll you in the copay program, in which you could pay as little as $0 per dose.*

If you’re uninsured or underinsured

We can help you find out if you qualify for the patient assistance program to cover your costs of therapy.

Nurse support icon

Nurse support

When enrolled in the ADVANCING Patient Support, you have access to a real nurse who can answer questions Monday–Friday (8 AM–8 PM ET) at no additional cost to you. In addition to answering questions about ZYNLONTA®, your nurse can help:

  • Prepare you for conversations with your doctor
  • Connect you to other support
  • Connect you to additional services

Welcome to ADVANCING Patient Support

After your doctor helps you enroll in ADVANCING Patient Support, we will give you a welcome call to introduce you to the program. Save 1-855-690-0340 in your contacts so you recognize the number when we call.

You can also call your dedicated Case Manager at 1-855-690-0340 Monday through Friday, 8 AM–8 PM ET if you have questions.

Other support

The Lymphoma Research Foundation (LRF) and the Leukemia & Lymphoma Society® (LSS) are great resources for information and support.

Leukemia & Lymphoma Society logo

Leukemia & Lymphoma Society®

A global leader in the fight against cancer, the Leukemia & Lymphoma Society® has invested more than a billion dollars in groundbreaking blood cancer research over the last 70+ years. They have a number of resources that those
with lymphoma and their caregivers can take advantage of, including:

  • Peer-to-Peer support with the free Patti Robinson Kaufmann First Connection® Program
  • Information Specialist Hotline: Monday through Friday, 9 AM–9 PM ET, 1-800-955-4572
  • Caregiver support with organizing worksheets and advice from specialists
  • Information on patient financial support programs
  • And even a podcast! See LLS.org for the full range of support and resources available

The Lymphoma Research Foundation logo

Lymphoma Research Foundation

The Lymphoma Research Foundation (https://lymphoma.org) is the nation’s largest nonprofit organization funding
lymphoma research and supporting the lymphoma community. They offer a wide range of resources to support those
with lymphoma and their loved ones, like:

  • The LRF Helpline — 800-500-9976 (Monday through Friday; 9:30 AM-7:30 PM ET) helpline@lymphoma.org
  • The Lymphoma Support Network – a peer support group for people with lymphoma and
    their caregivers that is over 6000 people strong.
  • Clinical Trials Information
  • Financial Support Guidance
  • Education Support
  • Webinars
  • And more

Additional support and resources

American Cancer Society
1-800-227-2345
www.cancer.org

Friend for Life Cancer
Support Network
1-866-374-3634
www.friend4life.org

Lymphoma Coalition
www.lymphomacoalition.org

Get info on technology

Antibody-Drug Conjugate — Also called ADC. A substance made up of a monoclonal antibody (also called mAb) that is chemically linked to a drug. The mAb binds to specific proteins found on certain types of cells, including cancer cells. The drug enters these cells and kills them. Some ADCs are used to treat cancer.

 
notebook
Learn how ZYNLONTA® targets cancer

ZYNLONTA® may cause
side effects

Study results icon
Read up on possible side effects
Expand

What is ZYNLONTA®?

ZYNLONTA® is a prescription medicine used to treat adults with certain types of large B-cell lymphoma that has come back (relapsed) or that did not respond to previous treatment (refractory), who have already received two or more treatments for their cancer.

It is not known if ZYNLONTA® is safe and effective in children.

The approval of ZYNLONTA® is based on a type of response rate. There is an ongoing study to confirm the clinical benefit of ZYNLONTA®.

IMPORTANT SAFETY INFORMATION

What are the possible side effects of ZYNLONTA®?

ZYNLONTA® may cause serious side effects, including:

  • Fluid retention. Your body may hold too much fluid during treatment with ZYNLONTA®. This can be serious. Tell your healthcare provider if you develop new or worsening swelling or puffiness, weight gain, chest pain, shortness of breath, or trouble breathing
  • Low blood cell counts (platelets, red blood cells, and white blood cells). Low blood cell counts are common with ZYNLONTA® but can also be serious or severe. Your healthcare provider will monitor your blood counts during treatment with ZYNLONTA®. Tell your healthcare provider right away if you get a fever of 100.4°F (38°C) or above, or any bruising or bleeding
  • Read full Important Safety Information
  • Infections. Serious infections, including infections that can cause death, have happened in people treated with ZYNLONTA®. Tell your healthcare provider right away if you have new or worsening signs or symptoms of infection
  • Skin reactions. Serious skin reactions have happened in people treated with ZYNLONTA®. Tell your healthcare provider if you get new or worsening skin reactions, including sensitivity to sunlight, skin rash, peeling, redness or irritation. You may burn more easily or get severe sunburns

The most common side effects of ZYNLONTA® include:

  • feeling tired or weak
  • skin rash
  • swelling
  • nausea
  • muscle or joint pain
  • increase in blood sugar (hyperglycemia)
  • changes in certain blood or laboratory tests

ZYNLONTA® may cause fertility problems in males which may affect your ability to father children. Talk to your healthcare provider if this is a concern for you. These are not all of the possible side effects of ZYNLONTA®.

What should I avoid while receiving ZYNLONTA®?

Avoid or limit your exposure to sunlight, including sunlight through glass, such as buildings or vehicle windows and artificial sunlight such as sunlamps or tanning beds. Exposure to sunlight during treatment with ZYNLONTA® can cause skin reaction or rash. Use sun protection measures such as sunscreen and wear loose-fitting clothes that cover your skin while out in sunlight.

Before you receive ZYNLONTA®, tell your healthcare provider about all of your medical conditions, including if you:

  • have an active infection or have had one recently
  • have liver problems
  • are pregnant or plan to become pregnant. ZYNLONTA® can harm your unborn baby

    Females who can become pregnant:

    • your healthcare provider may do a pregnancy test before starting treatment with ZYNLONTA®
    • you should use effective birth control (contraception) during treatment with ZYNLONTA® and for 10 months after the last dose of ZYNLONTA®. Talk to your healthcare provider about effective birth control. Tell your healthcare provider right away if you become pregnant or think that you are pregnant during treatment with ZYNLONTA®

    Males with female partners who can become pregnant:

    • you should use effective birth control (contraception) during treatment with ZYNLONTA® and for 7 months after the last dose of ZYNLONTA®
  • are breastfeeding or plan to breastfeed. It is not known if ZYNLONTA® passes into breast milk. Do not breastfeed during treatment with ZYNLONTA® and for 3 months after the last dose of ZYNLONTA®

Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of them to show your healthcare provider or pharmacist when you get new medicine.

You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to ADC Therapeutics at 1-855-690-0340.

Please see the full Prescribing Information for ZYNLONTA®, including Patient Information, for additional Important Safety Information.

What is ZYNLONTA®?

ZYNLONTA® is a prescription medicine used to treat adults with certain types of large B-cell lymphoma that has come back (relapsed) or that did not respond to previous treatment (refractory), who have already received two or more treatments for their cancer.

It is not known if ZYNLONTA® is safe and effective in children.

The approval of ZYNLONTA® is based on a type of response rate. There is an ongoing study to confirm the clinical benefit of ZYNLONTA®.

IMPORTANT SAFETY INFORMATION

What are the possible side effects of ZYNLONTA®?

ZYNLONTA® may cause serious side effects, including:

  • Fluid retention. Your body may hold too much fluid during treatment with ZYNLONTA®. This can be serious. Tell your healthcare provider if you develop new or worsening swelling or puffiness, weight gain, chest pain, shortness of breath, or trouble breathing
  • Low blood cell counts (platelets, red blood cells, and white blood cells). Low blood cell counts are common with ZYNLONTA® but can also be serious or severe. Your healthcare provider will monitor your blood counts during treatment with ZYNLONTA®. Tell your healthcare provider right away if you get a fever of 100.4°F (38°C) or above, or any bruising or bleeding
  • Read full Important Safety Information
  • Infections. Serious infections, including infections that can cause death, have happened in people treated with ZYNLONTA®. Tell your healthcare provider right away if you have new or worsening signs or symptoms of infection
  • Skin reactions. Serious skin reactions have happened in people treated with ZYNLONTA®. Tell your healthcare provider if you get new or worsening skin reactions, including sensitivity to sunlight, skin rash, peeling, redness or irritation. You may burn more easily or get severe sunburns

The most common side effects of ZYNLONTA® include:

  • feeling tired or weak
  • skin rash
  • swelling
  • nausea
  • muscle or joint pain
  • increase in blood sugar (hyperglycemia)
  • changes in certain blood or laboratory tests

ZYNLONTA® may cause fertility problems in males which may affect your ability to father children. Talk to your healthcare provider if this is a concern for you. These are not all of the possible side effects of ZYNLONTA®.

What should I avoid while receiving ZYNLONTA®?

Avoid or limit your exposure to sunlight, including sunlight through glass, such as buildings or vehicle windows and artificial sunlight such as sunlamps or tanning beds. Exposure to sunlight during treatment with ZYNLONTA® can cause skin reaction or rash. Use sun protection measures such as sunscreen and wear loose-fitting clothes that cover your skin while out in sunlight.

Before you receive ZYNLONTA®, tell your healthcare provider about all of your medical conditions, including if you:

  • have an active infection or have had one recently
  • have liver problems
  • are pregnant or plan to become pregnant. ZYNLONTA® can harm your unborn baby

    Females who can become pregnant:

    • your healthcare provider may do a pregnancy test before starting treatment with ZYNLONTA®
    • you should use effective birth control (contraception) during treatment with ZYNLONTA® and for 10 months after the last dose of ZYNLONTA®. Talk to your healthcare provider about effective birth control. Tell your healthcare provider right away if you become pregnant or think that you are pregnant during treatment with ZYNLONTA®

    Males with female partners who can become pregnant:

    • you should use effective birth control (contraception) during treatment with ZYNLONTA® and for 7 months after the last dose of ZYNLONTA®
  • are breastfeeding or plan to breastfeed. It is not known if ZYNLONTA® passes into breast milk. Do not breastfeed during treatment with ZYNLONTA® and for 3 months after the last dose of ZYNLONTA®

Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of them to show your healthcare provider or pharmacist when you get new medicine.

You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to ADC Therapeutics at 1-855-690-0340.

Please see the full Prescribing Information for ZYNLONTA®, including Patient Information, for additional Important Safety Information.