For US
residents only
US HealthcareProviders Site
ZYNLONTA™ is a prescription medicine used to treat adults with certain types of large B-cell lymphoma that has come back (relapsed) or that did not respond to previous treatment (refractory), who have already received two or more treatments for their cancer.
It is not known if ZYNLONTA™ is safe and effective in children.
ZYNLONTA™ is given by intravenous (IV) infusion by a trained healthcare provider at a clinic or infusion center.
You will receive an infusion once every 3 weeks.
Each infusion will last 30 minutes.
Your healthcare provider will decide how many treatment cycles you will receive.
Before every ZYNLONTA™ treatment, you may be given a prescription steroid to take twice a day for 3 days starting the day before your infusion. Your healthcare provider will determine if this is appropriate for you and may choose to give you the steroid as an oral medication or IV infusion.
ZYNLONTA™ may cause serious side effects, including:
fluid retention
low blood cell counts
infections
skin reactions
For more information on serious side effects, read the Important Safety Information.
The most common side effects of ZYNLONTA™ include:
feeling tired or weak
nausea
muscle or joint pain
skin rash
swelling
changes in certain blood or laboratory tests
These are not all the possible side effects of ZYNLONTA™. Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
The first place to find support is with your healthcare provider
There are also resources available from ADC Therapeutics, the maker of ZYNLONTA™, through ADVANCING Patient Support
To learn more about personalized assistance and support available through ADVANCING Patient Support, visit ADVANCINGPatientSupport.com or call 1-855-690-0340.
ZYNLONTA™ is a prescription medicine used to treat adults with certain types of large B-cell lymphoma that has come back (relapsed) or that did not respond to previous treatment (refractory), who have already received two or more treatments for their cancer.
It is not known if ZYNLONTA™ is safe and effective in children.
ZYNLONTA™ may cause serious side effects, including:
Fluid Retention: Your body may hold too much fluid during treatment with ZYNLONTA™. This can be serious. Tell your healthcare provider if you develop new or worsening swelling or puffiness, weight gain, chest pain, shortness of breath, or trouble breathing.
Low blood cell counts (platelets, red blood cells, and white blood cells). Low blood cell counts are common with ZYNLONTA™ but can also be serious or severe. Your healthcare provider will monitor your blood counts during treatment with ZYNLONTA™. Tell your healthcare provider right away if you get a fever of 100.4°F (38°C) or above, or any bruising or bleeding.
Infections: Serious infections, including infections that can cause death, have happened in people treated with ZYNLONTA™. Tell your healthcare provider right away if you have new or worsening signs or symptoms of infection.
Skin Reactions: Serious skin reactions have happened in people treated with ZYNLONTA™. Tell your healthcare provider if you get new or worsening skin reactions, including sensitivity to sunlight, skin rash, peeling, redness or irritation. You may burn more easily or get severe sunburns.
feeling tired or weak
skin rash
swelling
nausea
muscle or joint pain
increase in blood sugar (hyperglycemia)
changes in certain blood or laboratory tests
ZYNLONTA™ may cause fertility problems in males which may affect your ability to father children. Talk to your healthcare provider if this is a concern for you. These are not all of the possible side effects of ZYNLONTA™.
Avoid or limit your exposure to sunlight, including sunlight through glass, such as buildings or vehicle windows and artificial sunlight such as sunlamps or tanning beds. Exposure to sunlight during treatment with ZYNLONTA™ can cause skin reaction or rash. Use sun protection measures such as sunscreen and wear loose-fitting clothes that cover your skin while out in sunlight.
Before you receive ZYNLONTA™, tell your healthcare provider about all of your medical conditions, including if you:
have an active infection or have had one recently.
have liver problems.
are pregnant or plan to become pregnant. ZYNLONTA™ can harm your unborn baby.
Females who can become pregnant:
Your healthcare provider may do a pregnancy test before starting treatment with ZYNLONTA™.
You should use effective birth control (contraception) during treatment with ZYNLONTA™ and for 9 months after the last dose of ZYNLONTA™. Talk to your healthcare provider about effective birth control. Tell your healthcare provider right away if you become pregnant or think that you are pregnant during treatment with ZYNLONTA™.
Males with female partners who can become pregnant:
You should use effective birth control (contraception) during treatment with ZYNLONTA™ and for 6 months after the last dose of ZYNLONTA™.
are breastfeeding or plan to breastfeed. It is not known if ZYNLONTA™ passes into breast milk. Do not breastfeed during treatment with ZYNLONTA™ and for 3 months after the last dose of ZYNLONTA™.
Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of them to show your healthcare provider or pharmacist when you get new medicine.
You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to ADC Therapeutics at 1-855-690-0340.
Please see the full Prescribing Information for ZYNLONTA™, including Patient Information, for additional Important Safety Information.
ZYNLONTA™ is a prescription medicine used to treat adults with certain types of large B-cell lymphoma that has come back (relapsed) or that did not respond to previous treatment (refractory), who have already received two or more treatments for their cancer.
It is not known if ZYNLONTA™ is safe and effective in children.
ZYNLONTA™ may cause serious side effects, including:
Fluid Retention: Your body may hold too much fluid during treatment with ZYNLONTA™. This can be serious. Tell your healthcare provider if you develop new or worsening swelling or puffiness, weight gain, chest pain, shortness of breath, or trouble breathing.
Low blood cell counts (platelets, red blood cells, and white blood cells). Low blood cell counts are common with ZYNLONTA™ but can also be serious or severe. Your healthcare provider will monitor your blood counts during treatment with ZYNLONTA™. Tell your healthcare provider right away if you get a fever of 100.4°F (38°C) or above, or any bruising or bleeding.
Infections: Serious infections, including infections that can cause death, have happened in people treated with ZYNLONTA™. Tell your healthcare provider right away if you have new or worsening signs or symptoms of infection.
Skin Reactions: Serious skin reactions have happened in people treated with ZYNLONTA™. Tell your healthcare provider if you get new or worsening skin reactions, including sensitivity to sunlight, skin rash, peeling, redness or irritation. You may burn more easily or get severe sunburns.
feeling tired or weak
skin rash
swelling
nausea
muscle or joint pain
increase in blood sugar (hyperglycemia)
changes in certain blood or laboratory tests
ZYNLONTA™ may cause fertility problems in males which may affect your ability to father children. Talk to your healthcare provider if this is a concern for you. These are not all of the possible side effects of ZYNLONTA™.
Avoid or limit your exposure to sunlight, including sunlight through glass, such as buildings or vehicle windows and artificial sunlight such as sunlamps or tanning beds. Exposure to sunlight during treatment with ZYNLONTA™ can cause skin reaction or rash. Use sun protection measures such as sunscreen and wear loose-fitting clothes that cover your skin while out in sunlight.
Before you receive ZYNLONTA™, tell your healthcare provider about all of your medical conditions, including if you:
have an active infection or have had one recently.
have liver problems.
are pregnant or plan to become pregnant. ZYNLONTA™ can harm your unborn baby.
Females who can become pregnant:
Your healthcare provider may do a pregnancy test before starting treatment with ZYNLONTA™.
You should use effective birth control (contraception) during treatment with ZYNLONTA™ and for 9 months after the last dose of ZYNLONTA™. Talk to your healthcare provider about effective birth control. Tell your healthcare provider right away if you become pregnant or think that you are pregnant during treatment with ZYNLONTA™.
Males with female partners who can become pregnant:
You should use effective birth control (contraception) during treatment with ZYNLONTA™ and for 6 months after the last dose of ZYNLONTA™.
are breastfeeding or plan to breastfeed. It is not known if ZYNLONTA™ passes into breast milk. Do not breastfeed during treatment with ZYNLONTA™ and for 3 months after the last dose of ZYNLONTA™.
Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of them to show your healthcare provider or pharmacist when you get new medicine.
You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to ADC Therapeutics at 1-855-690-0340.
Please see the full Prescribing Information for ZYNLONTA™, including Patient Information, for additional Important Safety Information.
Select "OK" to continue or "Cancel" to stay on this site.